Pharmacotherapy of Neuropsychiatric Disturbances After TBI


  • Jonathan M. Silver
  • David B. Arciniegas
  • Christopher Byrne
  • Flora Hammond


Neuropsychiatric disturbances – that is, functionally limiting impairments of cognition, emotional regulation, and behavior – are among the most challenging and costly consequences of traumatic brain injury (TBI). Although systematic reviews, meta-analyses, and evidence-based guidelines for the non-pharmacologic and pharmacologic management of the cognitive, emotional, and behavioral sequelae of TBI have been developed and promulgated in peer-reviewed journals and conferences over the last decade, these guidelines are not well known to many physicians and other brain injury specialists and, as a result, are underused in everyday practice. Given the substantial effects of neuropsychiatric disturbances on everyday function and quality of life for persons with TBI and their families, and given the well-demonstrated excess costs attendant to such disturbances, there is a pressing need to provide physicians and other brain injury specialists with state-of-the-art information and evidence-based recommendations on the treatment of neuropsychiatric disturbances after TBI. The program seeks to meet this need through the provision of four lectures on the pharmacotherapy of neuropsychiatric disturbances among persons with TBI.

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